The average train between Karlsruhe and La Spezia takes 14h 20m and the fastest train takes 10h 20m. The train service runs several times per day from Karlsruhe to La Spezia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Karlsruhe and La Spezia. The earliest departure is at 4:03 AM at night, and the last departure from Karlsruhe is at 11:31 PM which arrives into La Spezia at 3:21 PM. All services require a transfer at Basel SBB and take an average of 14h 20m. The schedules shown below are for the next available departures.



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Want to know about travelling from Karlsruhe to La Spezia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlsruhe to La Spezia. However, there are services departing from Karlsruhe station and arriving at La Spezia station via Basel SBB. The journey, including transfers, takes approximately 14h 20m.
Karlsruhe to La Spezia train services, operated by Nederlandse Spoorwegen (NS), depart from Karlsruhe Hauptbahnhof station.
Karlsruhe to La Spezia train services, operated by Nederlandse Spoorwegen (NS), arrive at La Spezia Centrale station.
Book your Karlsruhe to La Spezia train tickets online with Nederlandse Spoorwegen (NS), Swiss Federal Railways (SBB CFF FFS) and 4 other operators.
The distance between Karlsruhe and La Spezia is 556.2 km. The road distance is 747 km.
You can take a train from Karlsruhe Hauptbahnhof to La Spezia Centrale via Basel SBB, Lugano, and Milano Centrale in around 11h 27m.