The average train between Karlsruhe and Lausanne takes 4h 53m and the fastest train takes 4h 30m. There is a train service every few hours from Karlsruhe to Lausanne. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Karlsruhe and Lausanne. The earliest departure is at 4:03 AM at night, and the last departure from Karlsruhe is at 7:01 PM which arrives into Lausanne at 11:56 PM. All services require a transfer, and take on average 4h 53m. The schedules shown below are for the next available departures.

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4h 53m • 1 change

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Want to know about travelling from Karlsruhe to Lausanne? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlsruhe to Lausanne. However, there are services departing from Karlsruhe station and arriving at Lausanne station via Basel SBB. The journey, including transfers, takes approximately 4h 53m.
Karlsruhe to Lausanne train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
Karlsruhe to Lausanne train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Lausanne station.
Book your Karlsruhe to Lausanne train tickets online with Deutsche Bahn Intercity (DB IC), Swiss Federal Railways (SBB CFF FFS) and 2 other operators.
The distance between Karlsruhe and Lausanne is 307.2 km. The road distance is 371 km.
You can take a train from Karlsruhe Hauptbahnhof to Lausanne via Basel SBB in around 4h 44m.