The average train between Karlsruhe and Lucerne takes 3h 16m and the fastest train takes 3h 4m. The train service runs several times per day from Karlsruhe to Lucerne. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Karlsruhe and Lucerne. The earliest departure is at 4:03 AM at night, and the last departure from Karlsruhe is at 9:26 PM which arrives into Lucerne at 1:16 AM. All services require a transfer, and take on average 3h 16m. The schedules shown below are for the next available departures.

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Want to know about travelling from Karlsruhe to Lucerne? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlsruhe to Lucerne. However, there are services departing from Karlsruhe station and arriving at Lucerne station via Basel SBB. The journey, including transfers, takes approximately 3h 16m.
Karlsruhe to Lucerne train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
Karlsruhe to Lucerne train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Luzern station.
Book your Karlsruhe to Lucerne train tickets online with Deutsche Bahn Intercity (DB IC), Swiss Federal Railways (SBB CFF FFS) and 3 other operators.
The distance between Karlsruhe and Lucerne is 217.9 km. The road distance is 286 km.
You can take a train from Karlsruhe Hauptbahnhof to Luzern via Basel SBB in around 3h 26m.