The average train between Karlsruhe and Mülheim takes 3h 20m and the fastest train takes 3h 5m. The train service runs several times per day from Karlsruhe to Mülheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Karlsruhe and Mülheim. The earliest departure is at 6:59 AM in the morning, and the last departure from Karlsruhe is at 8:59 PM which arrives into Mülheim at 12:20 AM. All services require a transfer, and take on average 3h 20m. The schedules shown below are for the next available departures.

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Want to know about travelling from Karlsruhe to Mülheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlsruhe to Mülheim. However, there are services departing from Karlsruhe station and arriving at Mülheim station via Duisburg Hbf. The journey, including transfers, takes approximately 3h 20m.
Karlsruhe to Mülheim train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
Karlsruhe to Mülheim train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Duisburg Hbf station.
Book your Karlsruhe to Mülheim train tickets online with Deutsche Bahn Intercity (DB IC), National Express and Deutsche Bahn Regio (DB Regional).
The distance between Karlsruhe and Mülheim is 290.4 km. The road distance is 372 km.
Deutsche Bahn Intercity (DB IC) operates a train from Karlsruhe Hauptbahnhof to Duisburg Hbf every 4 hours. Tickets cost €65–280 and the journey takes 2h 46m.