Karlsruhe to Mainz, Hauptbahnhof train times
Trains run hourly between Karlsruhe and Mainz, Hauptbahnhof. The earliest departure is at 12:28 AM at night, and the last departure from Karlsruhe is at 9:59 PM which arrives into Mainz, Hauptbahnhof at 11:53 PM. All services require a transfer, and take on average 1h 54m. The schedules shown below are for the next available departures.
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1h 44m • 1 change
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1h 19m • 1 change
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1h 59m • 1 change
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1h 44m • 1 change
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Departing Tuesday, August 18, 2026
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3h 19m • 1 change
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4h 14m • 1 change
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2h 43m • 1 change
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2h 10m • 1 change
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Departing Wednesday, August 19, 2026
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3h 19m • 1 change
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4h 14m • 1 change
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2h 43m • 1 change
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2h 10m • 1 change
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#/media/File:ICE_4_Berlin_Hauptbahnhof_(3).jpg "ICE 4 Berlin Hauptbahnhof")
