The average train between Karlsruhe and Milan takes 7h 18m and the fastest train takes 6h 16m. The train service runs several times per day from Karlsruhe to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Karlsruhe and Milan. The earliest departure is at 4:03 AM at night, and the last departure from Karlsruhe is at 7:01 PM which arrives into Milan at 7:17 AM. All services require a transfer at Basel SBB and take an average of 7h 18m. The schedules shown below are for the next available departures.


7h 14m • 2 changes


6h 16m • 2 changes


6h 16m • 2 changes


6h 16m • 2 changes


7h 13m • 2 changes


6h 16m • 2 changes


6h 16m • 2 changes


6h 16m • 2 changes


7h 14m • 2 changes


6h 16m • 2 changes


6h 16m • 2 changes


6h 16m • 2 changes


7h 14m • 2 changes


6h 16m • 2 changes


6h 16m • 2 changes


6h 16m • 2 changes
Want to know about travelling from Karlsruhe to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlsruhe to Milan. However, there are services departing from Karlsruhe station and arriving at Milan station via Basel SBB. The journey, including transfers, takes approximately 7h 18m.
Karlsruhe to Milan train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
Karlsruhe to Milan train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Milano Centrale station.
Book your Karlsruhe to Milan train tickets online with Deutsche Bahn Intercity (DB IC), Swiss Federal Railways (SBB CFF FFS) and 2 other operators.
The distance between Karlsruhe and Milan is 398.6 km. The road distance is 522 km.
You can take a train from Karlsruhe Hauptbahnhof to Milano Centrale via Basel SBB and Lugano in around 7h 40m.