The average train between Karlsruhe and Nijmegen takes 5h 33m and the fastest train takes 4h 48m. The train service runs several times per day from Karlsruhe to Nijmegen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Karlsruhe and Nijmegen. The earliest departure is at 5:59 AM in the morning, and the last departure from Karlsruhe is at 9:59 PM which arrives into Nijmegen at 8:47 AM. All services require a transfer at Frankfurt and take an average of 5h 33m. The schedules shown below are for the next available departures.


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4h 48m • 2 changesWant to know about travelling from Karlsruhe to Nijmegen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlsruhe to Nijmegen. However, there are services departing from Karlsruhe station and arriving at Nijmegen station via Frankfurt. The journey, including transfers, takes approximately 5h 33m.
Karlsruhe to Nijmegen train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
Karlsruhe to Nijmegen train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Arnhem Centraal station.
Book your Karlsruhe to Nijmegen train tickets online with Deutsche Bahn Intercity (DB IC) and Nederlandse Spoorwegen (NS).
The distance between Karlsruhe and Nijmegen is 363.2 km. The road distance is 498 km.
You can take a train from Karlsruhe Hauptbahnhof to Nijmegen via Frankfurt and Arnhem Centraal in around 5h 11m.