The average train between Karlsruhe and Pilsen takes 8h 53m and the fastest train takes 7h 41m. The train service runs several times per day from Karlsruhe to Pilsen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Karlsruhe and Pilsen. The earliest departure is at 7:06 AM in the morning, and the last departure from Karlsruhe is at 7:06 PM which arrives into Pilsen at 8:47 AM. All services require a transfer at Nürnberg Hbf and take an average of 8h 53m. The schedules shown below are for the next available departures.


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7h 41m • 2 changesWant to know about travelling from Karlsruhe to Pilsen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlsruhe to Pilsen. However, there are services departing from Karlsruhe station and arriving at Pilsen station via Nürnberg Hbf. The journey, including transfers, takes approximately 8h 53m.
Karlsruhe to Pilsen train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
Karlsruhe to Pilsen train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Plzen Hlavni Nadrazi station.
Book your Karlsruhe to Pilsen train tickets online with Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) and Die Länderbahn.
The distance between Karlsruhe and Pilsen is 369.2 km. The road distance is 523 km.
You can take a train from Karlsruhe Hauptbahnhof to Plzen Hlavni Nadrazi via Nürnberg Hbf, Nürnberg Hbf, and Schwandorf in around 7h 44m.