The average train between Karlsruhe and Rome takes 12h 41m and the fastest train takes 10h 4m. The train service runs several times per day from Karlsruhe to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Karlsruhe and Rome. The earliest departure is at 4:03 AM at night, and the last departure from Karlsruhe is at 11:26 PM which arrives into Rome at 1:35 PM. All services require a transfer at Basel SBB and take an average of 12h 41m. The schedules shown below are for the next available departures.



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Want to know about travelling from Karlsruhe to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlsruhe to Rome. However, there are services departing from Karlsruhe station and arriving at Rome station via Basel SBB. The journey, including transfers, takes approximately 12h 41m.
Karlsruhe to Rome train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
Karlsruhe to Rome train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Roma Termini station.
Book your Karlsruhe to Rome train tickets online with Deutsche Bahn Intercity (DB IC), Swiss Federal Railways (SBB CFF FFS) and 2 other operators.
The distance between Karlsruhe and Rome is 852.2 km. The road distance is 1,103 km.
You can take a train from Karlsruhe Hauptbahnhof to Roma Termini via Basel SBB, Lugano, and Milano Centrale in around 11h.