The average train between Karlsruhe and Senigallia takes 15h 35m and the fastest train takes 10h 3m. The train service runs several times per day from Karlsruhe to Senigallia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Karlsruhe and Senigallia. The earliest departure is at 4:03 AM at night, and the last departure from Karlsruhe is at 7:01 PM which arrives into Senigallia at 12:01 PM. All services require a transfer at Basel SBB and take an average of 15h 35m. The schedules shown below are for the next available departures.




11h 13m • 4 changes




10h 50m • 4 changes
Arrives next day




19h 51m • 4 changes
Arrives next day




19h 7m • 4 changes




11h 13m • 4 changes




10h 3m • 4 changes
Arrives next day




19h 51m • 4 changes
Arrives next day




19h 7m • 4 changes
Want to know about travelling from Karlsruhe to Senigallia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlsruhe to Senigallia. However, there are services departing from Karlsruhe station and arriving at Senigallia station via Basel SBB. The journey, including transfers, takes approximately 15h 35m.
Karlsruhe to Senigallia train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
Karlsruhe to Senigallia train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Senigallia station.
Book your Karlsruhe to Senigallia train tickets online with Deutsche Bahn Intercity (DB IC), Swiss Federal Railways (SBB CFF FFS) and 6 other operators.
The distance between Karlsruhe and Senigallia is 694.2 km. The road distance is 913 km.
You can take a train from Karlsruhe Hauptbahnhof to Senigallia via Basel SBB, Lugano, Milano Centrale, and Bologna Centrale in around 11h 36m.