The average train between Karlsruhe and Zwickau takes 6h 55m and the fastest train takes 6h 1m. The train service runs several times per day from Karlsruhe to Zwickau. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Karlsruhe and Zwickau. The earliest departure is at 5:59 AM in the morning, and the last departure from Karlsruhe is at 9:59 PM which arrives into Zwickau at 10:55 AM. All services require a transfer at Frankfurt and take an average of 6h 55m. The schedules shown below are for the next available departures.


6h 31m • 2 changes

6h 9m • 2 changes

6h 1m • 2 changes

6h 7m • 2 changes

6h 9m • 2 changes

6h 18m • 2 changes

6h 9m • 2 changes

6h 18m • 2 changes

6h 9m • 2 changes

6h 18m • 2 changes

6h 9m • 2 changes

6h 18m • 2 changes

6h 9m • 2 changes

6h 18m • 2 changes

6h 9m • 2 changes

6h 18m • 2 changes

6h 9m • 2 changes

6h 18m • 2 changes

6h 9m • 2 changes

6h 18m • 2 changesWant to know about travelling from Karlsruhe to Zwickau? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlsruhe to Zwickau. However, there are services departing from Karlsruhe station and arriving at Zwickau station via Frankfurt. The journey, including transfers, takes approximately 6h 55m.
Karlsruhe to Zwickau train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
Karlsruhe to Zwickau train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Zwickau, Hauptbahnhof station.
Book your Karlsruhe to Zwickau train tickets online with Deutsche Bahn Intercity (DB IC) and Deutsche Bahn Regio (DB Regional).
The distance between Karlsruhe and Zwickau is 349.4 km. The road distance is 594 km.
You can take a train from Karlsruhe Hauptbahnhof to Zwickau, Hauptbahnhof via Frankfurt and Leipzig Hbf in around 6h 34m.