The average train between La Défense and Lille takes 1h 25m and the fastest train takes 1h 20m. The train service runs several times per day from La Défense to Lille. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between La Défense and Lille. The earliest departure is at 7:25 AM in the morning, and the last departure from La Défense is at 9:37 PM which arrives into Lille at 11:17 PM. All services require a transfer at Gare Magenta and take an average of 1h 25m. The schedules shown below are for the next available departures.

1h 22m • 1 change

1h 20m • 1 change

1h 27m • 1 change

1h 29m • 1 change

1h 22m • 1 change

1h 20m • 1 change

1h 27m • 1 change

1h 29m • 1 change

1h 22m • 1 change

1h 20m • 1 change

1h 20m • 1 change

1h 29m • 1 change

1h 23m • 1 change

1h 26m • 1 change

1h 31m • 1 change

1h 20m • 1 change

1h 25m • 1 change

1h 25m • 1 change

1h 26m • 1 change

1h 26m • 1 change

1h 22m • 1 change

1h 27m • 1 change

1h 29m • 1 change

1h 22m • 1 change
Want to know about travelling from La Défense to Lille? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from La Défense to Lille. However, there are services departing from La Défense station and arriving at Lille station via Lille Flandres. The journey, including transfers, takes approximately 1h 25m.
La Défense to Lille train services, operated by Société Nationale des Chemins de fer Français (SNCF), depart from Paris Nord station.
La Défense to Lille train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Lille Flandres station.
The distance between La Défense and Lille is 202.3 km. The road distance is 236 km.
TGV inOui operates a train from Paris Nord to Lille Flandres hourly. Tickets cost €45–75 and the journey takes 1h 8m. Société Nationale des Chemins de fer Français (SNCF) also services this route once daily.