The average train between La Mesa and Los Angeles takes 3h 47m and the fastest train takes 3h 33m. There is a train service every few hours from La Mesa to Los Angeles. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between La Mesa and Los Angeles. The earliest departure is at 12:09 AM at night, and the last departure from La Mesa is at 8:24 PM which arrives into Los Angeles at 11:57 PM. All services require a transfer at Old Town Station and take an average of 3h 47m. The schedules shown below are for the next available departures.

3h 33m • 1 change

3h 33m • 1 change

3h 33m • 1 change

3h 33m • 1 change

6h 48m • 1 change

3h 33m • 1 change

3h 33m • 1 change

3h 33m • 1 change

6h 48m • 1 change

3h 33m • 1 change

3h 33m • 1 change

3h 33m • 1 change

6h 48m • 1 change

3h 33m • 1 change

3h 33m • 1 change

3h 33m • 1 change
Want to know about travelling from La Mesa to Los Angeles? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from La Mesa to Los Angeles. However, there are services departing from La Mesa station and arriving at Los Angeles station via Los Angeles. The journey, including transfers, takes approximately 3h 47m.
La Mesa to Los Angeles train services, operated by San Diego Metro Transit, depart from San Diego Old Town Transportation Center station.
La Mesa to Los Angeles train services, operated by San Diego Metro Transit, arrive at Los Angeles station.
The distance between La Mesa and Los Angeles is 182.3 km. The road distance is 216 km.
Amtrak operates a train from San Diego Old Town Transportation Center to Los Angeles hourly. Tickets cost $40–85 and the journey takes 2h 47m.