The average train between La Seyne-sur-Mer and Lyon takes 3h 8m and the fastest train takes 2h 42m. There is a train service every few hours from La Seyne-sur-Mer to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between La Seyne-sur-Mer and Lyon. The earliest departure is at 5:32 AM in the morning, and the last departure from La Seyne-sur-Mer is at 11:33 PM which arrives into Lyon at 8:20 AM. All services require a transfer, and take on average 3h 8m. The schedules shown below are for the next available departures.

3h • 1 change

2h 58m • 1 change
Arrives next day

9h 48m • 1 change

2h 51m • 1 change

3h 25m • 1 change

2h 49m • 1 change

2h 44m • 1 change

3h 17m • 1 change

2h 51m • 1 change

3h 25m • 1 change

3h 7m • 1 change

2h 48m • 1 change

2h 51m • 1 change

2h 55m • 1 change

3h 7m • 1 change

2h 48m • 1 change

2h 47m • 1 change

2h 51m • 1 change

2h 55m • 1 change
Want to know about travelling from La Seyne-sur-Mer to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from La Seyne-sur-Mer to Lyon. However, there are services departing from La Seyne-sur-Mer station and arriving at Lyon station via Marseille St Charles. The journey, including transfers, takes approximately 3h 8m.
La Seyne-sur-Mer to Lyon train services, operated by Zou! Lignes Express Régionales, depart from La Seyne - Six-Fours station.
La Seyne-sur-Mer to Lyon train services, operated by Zou! Lignes Express Régionales, arrive at Lyon Part Dieu station.
Book your La Seyne-sur-Mer to Lyon train tickets online with Zou! Lignes Express Régionales and TGV inOui.
The distance between La Seyne-sur-Mer and Lyon is 305.3 km. The road distance is 381 km.
You can take a train from La Seyne - Six-Fours to Lyon Part Dieu via Marseille St Charles in around 2h 57m.