The average train between La Spezia and Acqui Terme takes 3h 29m and the fastest train takes 2h 53m. The train service runs several times per day from La Spezia to Acqui Terme. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between La Spezia and Acqui Terme. The earliest departure is at 4:56 AM at night, and the last departure from La Spezia is at 11:27 PM which arrives into Acqui Terme at 7:26 AM. All services require a transfer, and take on average 3h 29m. The schedules shown below are for the next available departures.

3h 54m • 1 change

3h • 1 change

2h 56m • 1 change

3h 1m • 1 change

3h 39m • 1 change

3h 1m • 1 change

3h 54m • 1 change

3h • 1 change

3h 39m • 1 change

3h 1m • 1 change

3h 54m • 1 change

3h • 1 change

3h 39m • 1 change

3h 1m • 1 change

3h 54m • 1 change

3h • 1 change

3h 39m • 1 change

3h 1m • 1 change

3h 54m • 1 change

3h • 1 change
Want to know about travelling from La Spezia to Acqui Terme? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from La Spezia to Acqui Terme. However, there are services departing from La Spezia station and arriving at Acqui Terme station via Genova Brignole. The journey, including transfers, takes approximately 3h 29m.
La Spezia to Acqui Terme train services, operated by Trenitalia, depart from La Spezia Centrale station.
La Spezia to Acqui Terme train services, operated by Trenitalia, arrive at Acqui Terme station.
Book your La Spezia to Acqui Terme train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between La Spezia and Acqui Terme is 125 km. The road distance is 145 km.
You can take a train from La Spezia Centrale to Acqui Terme via Genova Brignole in around 2h 56m.