Lago di Como to Isernia Trains

Lago di Como to Isernia trains

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Trip Overview

The average train between Lago di Como and Isernia takes 9h 17m and the fastest train takes 6h 47m. The train service runs several times per day from Lago di Como to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

9h 17m
Duration: 794 km
Distance: €137
Average price: 4 times a day
Frequency

Train

best

Take the train from Como S. Giovanni to Milano Centraletrain S11
Take the train from Milano Centrale to Roma Terminitrain Fr / ...
Take the train from Roma Termini to Iserniatrain Re

7h 6m

€105–193

Lago di Como to Isernia train times

Trains run 4 times a day between Lago di Como and Isernia. The earliest departure is at 8:36 AM in the morning, and the last departure from Lago di Como is at 9:36 PM which arrives into Isernia at 11:15 AM. All services require a transfer at Milano Centrale and take an average of 9h 17m. The schedules shown below are for the next available departures.

Departing Sunday, October 25, 2026

7:36 PM → 8:27 AM
Arrives next day
12h 51m • 2 changes
9:36 PM → 11:15 AM
Arrives next day
13h 39m • 2 changes

Departing Monday, October 26, 2026

8:36 AM → 3:23 PM
6h 47m • 2 changes
9:36 AM → 4:40 PM
7h 4m • 2 changes
3:36 PM → 10:26 PM
6h 50m • 2 changes
7:36 PM → 8:27 AM
Arrives next day
12h 51m • 2 changes
Show more

Departing Tuesday, October 27, 2026

8:36 AM → 3:23 PM
6h 47m • 2 changes
9:36 AM → 4:40 PM
7h 4m • 2 changes
3:36 PM → 10:26 PM
6h 50m • 2 changes
7:36 PM → 8:27 AM
Arrives next day
12h 51m • 2 changes
Show more

Departing Wednesday, October 28, 2026

8:36 AM → 3:23 PM
6h 47m • 2 changes
9:36 AM → 4:40 PM
7h 4m • 2 changes
3:36 PM → 10:26 PM
6h 50m • 2 changes
7:36 PM → 8:27 AM
Arrives next day
12h 51m • 2 changes
Show more

Departing Thursday, October 29, 2026

8:36 AM → 3:23 PM
6h 47m • 2 changes
9:36 AM → 4:40 PM
7h 4m • 2 changes
3:36 PM → 10:26 PM
6h 50m • 2 changes
7:36 PM → 8:27 AM
Arrives next day
12h 51m • 2 changes
Show more

Departing Friday, October 30, 2026

8:36 AM → 3:23 PM
6h 47m • 2 changes
9:36 AM → 4:40 PM
7h 4m • 2 changes
3:36 PM → 10:26 PM
6h 50m • 2 changes
7:36 PM → 8:27 AM
Arrives next day
12h 51m • 2 changes

Departing Saturday, October 31, 2026

8:36 AM → 3:23 PM
6h 47m • 2 changes
9:36 AM → 4:40 PM
7h 4m • 2 changes
3:36 PM → 10:26 PM
6h 50m • 2 changes

Frequently asked questions

Want to know about travelling from Lago di Como to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.