The average train between Lago di Como and Siena takes 5h 37m and the fastest train takes 5h 1m. There is a train service every few hours from Lago di Como to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Lago di Como and Siena. The earliest departure is at 4:36 AM at night, and the last departure from Lago di Como is at 7:36 PM which arrives into Siena at 7:55 AM. All services require a transfer at Milano Centrale and take an average of 5h 37m. The schedules shown below are for the next available departures.


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Want to know about travelling from Lago di Como to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lago di Como to Siena. However, there are services departing from Lago di Como station and arriving at Siena station via Milano Centrale. The journey, including transfers, takes approximately 5h 37m.
Lago di Como to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Como S. Giovanni station.
Lago di Como to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Siena station.
Book your Lago di Como to Siena train tickets online with Swiss Federal Railways (SBB CFF FFS), Trenitalia Frecce and Trenitalia.
The distance between Lago di Como and Siena is 340.9 km. The road distance is 444 km.
You can take a train from Como S. Giovanni to Siena via Milano Centrale and Firenze S.M.N. in around 4h 49m.