The average train between Lake Iseo and Rome takes 6h 20m and the fastest train takes 5h 3m. The train service runs several times per day from Lake Iseo to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Lake Iseo and Rome. The earliest departure is at 6:22 AM in the morning, and the last departure from Lake Iseo is at 9:23 PM which arrives into Rome at 11:00 AM. All services require a transfer at Brescia and take an average of 6h 20m. The schedules shown below are for the next available departures.
Arrives next day


12h 57m • 2 changesArrives next day


13h 37m • 2 changes

5h 57m • 2 changes

5h 47m • 2 changes

6h 8m • 2 changes

5h 57m • 2 changes

5h 57m • 2 changes

5h 47m • 2 changes

6h 8m • 2 changes

5h 57m • 2 changes

5h 57m • 2 changes

5h 47m • 2 changes

6h 8m • 2 changes

5h 57m • 2 changes

5h 57m • 2 changes

5h 47m • 2 changes

6h 8m • 2 changes

5h 57m • 2 changesWant to know about travelling from Lake Iseo to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lake Iseo to Rome. However, there are services departing from Lake Iseo station and arriving at Rome station via Milano Centrale. The journey, including transfers, takes approximately 6h 20m.
Lake Iseo to Rome train services, operated by Trenord, depart from Brescia station.
Lake Iseo to Rome train services, operated by Trenord, arrive at Roma Termini station.
Book your Lake Iseo to Rome train tickets online with Trenord, Trenitalia Frecce and ItaloTreno.
The distance between Lake Iseo and Rome is 467 km. The road distance is 694 km.
You can take a train from Sulzano to Roma Termini via Brescia and Milano Centrale in around 4h 56m.