The average train between Lake Iseo and Rome takes 7h 44m and the fastest train takes 5h 24m. The train service runs several times per day from Lake Iseo to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Lake Iseo and Rome. The earliest departure is at 6:55 AM in the morning, and the last departure from Lake Iseo is at 9:23 PM which arrives into Rome at 11:00 AM. All services require a transfer at Brescia and take an average of 7h 44m. The schedules shown below are for the next available departures.


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6h 7m • 2 changesWant to know about travelling from Lake Iseo to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lake Iseo to Rome. However, there are services departing from Brescia station and arriving at Roma Termini station via Milano Centrale station. The journey, including transfers, takes approximately 7h 44m.
Lake Iseo to Rome train services, operated by ItaloTreno, depart from Brescia station.
Lake Iseo to Rome train services, operated by ItaloTreno, arrive at Roma Termini station.
Book your Lake Iseo to Rome train tickets online with Omio.
The distance between Lake Iseo and Rome is 467 km. The road distance is 555 km.
You can take a train from Sulzano to Roma Termini via Brescia and Milano Centrale in around 5h 7m.