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Lawrence to Buffalo trains

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Trip Overview

The average train between Lawrence and Buffalo takes 30h 42m and the fastest train takes 27h 53m. The train runs, on average, 5 times per week from Lawrence to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

30h 42m
Duration
524 mi
Distance
$361
Average price
5 times a week
Frequency

Lawrence to Buffalo train times

Trains run 5 times a week between Lawrence and Buffalo. The earliest departure is at 11:37 AM in the morning, and the last departure from Lawrence is at 9:30 PM which arrives into Buffalo at 3:30 PM. All services require a transfer at Oak Grove and take an average of 30h 42m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    MBTAMBTAAmtrakVIA Rail27h 53m • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    MBTAMBTAAmtrakVIA Rail27h 53m • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    MBTAMBTAAmtrakVIA Rail27h 53m • 3 changes
  •  → 

    Arrives +2 days

    MBTAMBTAAmtrakVIA Rail42h • 3 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    MBTAMBTAAmtrakVIA Rail27h 53m • 3 changes

Frequently asked questions

Want to know about travelling from Lawrence to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Lawrence to Buffalo.ExpandLaunch map view
  • Distance: 523.6 mi
  • Duration: 30h 42m

What companies run services between Lawrence, MA, USA and Buffalo, NY, USA?

Amtrak operates a train from Boston to Buffalo Depew Station once daily. Tickets cost $260–420 and the journey takes 11h 32m.

Operators