The average train between León and Santander takes 4h 22m and the fastest train takes 3h 51m. The train service runs several times per day from León to Santander. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between León and Santander. The earliest departure is at 8:14 AM in the morning, and the last departure from León is at 6:58 PM which arrives into Santander at 11:15 PM. All services require a transfer, and take on average 4h 22m. The schedules shown below are for the next available departures.

3h 52m • 1 change

4h 29m • 1 change

4h 38m • 1 change

4h 30m • 1 change

3h 52m • 1 change

4h 29m • 1 change

4h 38m • 1 change

4h 30m • 1 change
Want to know about travelling from León to Santander? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from León to Santander. However, there are services departing from León station and arriving at Santander station via Palencia. The journey, including transfers, takes approximately 4h 22m.
León to Santander train services, operated by Renfe Viajeros, depart from Leon station.
León to Santander train services, operated by Renfe Viajeros, arrive at Santander station.
Book your León to Santander train tickets online with Renfe Viajeros and Renfe AVE.
The distance between León and Santander is 172.8 km. The road distance is 328 km.
You can take a train from Leon to Santander via Palencia in around 4h 20m.