The average train between Leiden and Enschede takes 2h 35m and the fastest train takes 2h 27m. There is an hourly train service from Leiden to Enschede. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Leiden and Enschede. The earliest departure is at 4:40 AM at night, and the last departure from Leiden is at 11:16 PM which arrives into Enschede at 1:44 AM. All services require a transfer, and take on average 2h 35m. The schedules shown below are for the next available departures.

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2h 30m • 1 changeWant to know about travelling from Leiden to Enschede? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Leiden to Enschede. However, there are services departing from Leiden Centraal station and arriving at Enschede station via Utrecht Centraal station. The journey, including transfers, takes approximately 2h 35m.
Leiden to Enschede train services, operated by Nederlandse Spoorwegen (NS), depart from Leiden Centraal station.
Leiden to Enschede train services, operated by Nederlandse Spoorwegen (NS), arrive at Enschede station.
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The distance between Leiden and Enschede is 163.9 km. The road distance is 189 km.
You can take a train from Leiden Centraal to Enschede via Utrecht Centraal in around 3h 29m.