The average train between Lille and La Défense takes 1h 27m and the fastest train takes 1h 17m. The train service runs several times per day from Lille to La Défense. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Lille and La Défense. The earliest departure is at 5:52 AM in the morning, and the last departure from Lille is at 8:12 PM which arrives into La Défense at 9:32 PM. All services require a transfer at Paris Nord and take an average of 1h 27m. The schedules shown below are for the next available departures.

1h 33m • 1 change

1h 22m • 1 change

1h 21m • 1 change

1h 20m • 1 change

1h 33m • 1 change

1h 22m • 1 change

1h 21m • 1 change

1h 20m • 1 change

1h 33m • 1 change

1h 21m • 1 change

1h 20m • 1 change

1h 19m • 1 change

1h 28m • 1 change

1h 20m • 1 change

3h 7m • 1 change

1h 19m • 1 change

1h 20m • 1 change

1h 39m • 1 change

1h 23m • 1 change

1h 18m • 1 change

1h 33m • 1 change

1h 22m • 1 change

1h 21m • 1 change

1h 32m • 1 change
Want to know about travelling from Lille to La Défense? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lille to La Défense. However, there are services departing from Lille station and arriving at La Défense station via Paris Nord. The journey, including transfers, takes approximately 1h 27m.
Lille to La Défense train services, operated by TGV inOui, depart from Lille Flandres station.
Lille to La Défense train services, operated by TGV inOui, arrive at Paris Nord station.
The distance between Lille and La Défense is 202.3 km. The road distance is 236 km.
TGV inOui operates a train from Lille Flandres to Paris Nord hourly. Tickets cost €45–75 and the journey takes 1h 5m. Société Nationale des Chemins de fer Français (SNCF) also services this route once daily.