The average train between Little Italy and Boston takes 4h 27m and the fastest train takes 4h. There is a train service every few hours from Little Italy to Boston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Little Italy and Boston. The earliest departure is at 2:43 AM at night, and the last departure from Little Italy is at 7:36 PM which arrives into Boston at 12:15 AM. All services require a transfer at 34 St-Herald Sq and take an average of 4h 27m. The schedules shown below are for the next available departures.

4h 41m • 1 change

4h 5m • 1 change

4h 14m • 1 change
Arrives next day

4h 38m • 1 change

4h 28m • 1 change

4h 41m • 1 change

4h 16m • 1 change

4h • 1 change

4h 28m • 1 change

4h 41m • 1 change

4h 16m • 1 change

4h • 1 change

4h 28m • 1 change

4h 41m • 1 change

4h 16m • 1 change

4h • 1 change
Want to know about travelling from Little Italy to Boston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Little Italy to Boston. However, there are services departing from Little Italy station and arriving at Boston station via Boston. The journey, including transfers, takes approximately 4h 27m.
Little Italy to Boston train services, operated by MTA, depart from Ny Moynihan Train Hall At Penn Station.
Little Italy to Boston train services, operated by MTA, arrive at Boston station.
The distance between Little Italy and Boston is 304.7 km. The road distance is 378 km.
Amtrak Acela operates a train from Ny Moynihan Train Hall At Penn Station to Boston every 4 hours. Tickets cost $50–750 and the journey takes 3h 47m. Amtrak also services this route every 3 hours.