The average train between Los Angeles and La Mesa takes 3h 39m and the fastest train takes 3h 24m. There is a train service every few hours from Los Angeles to La Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Los Angeles and La Mesa. The earliest departure is at 6:10 AM in the morning, and the last departure from Los Angeles is at 10:10 PM which arrives into La Mesa at 5:04 AM. All services require a transfer at San Diego Old Town Transportation Center and take an average of 3h 39m. The schedules shown below are for the next available departures.

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Want to know about travelling from Los Angeles to La Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Los Angeles to La Mesa. However, there are services departing from Los Angeles station and arriving at La Mesa station via San Diego Old Town Transportation Center. The journey, including transfers, takes approximately 3h 39m.
Los Angeles to La Mesa train services, operated by Amtrak, depart from Los Angeles station.
Los Angeles to La Mesa train services, operated by Amtrak, arrive at San Diego Old Town Transportation Center station.
The distance between Los Angeles and La Mesa is 182.3 km. The road distance is 216 km.
Amtrak operates a train from Los Angeles to San Diego Old Town Transportation Center hourly. Tickets cost $40–85 and the journey takes 2h 42m.