The average train between Lucerne and Frankfurt am Main takes 4h 54m and the fastest train takes 4h 15m. The train service runs several times per day from Lucerne to Frankfurt am Main. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Lucerne and Frankfurt am Main. The earliest departure is at 12:47 AM at night, and the last departure from Lucerne is at 11:54 PM which arrives into Frankfurt am Main at 7:40 AM. All services require a transfer, and take on average 4h 54m. The schedules shown below are for the next available departures.

4h 15m • 1 change

5h 15m • 1 change

5h 15m • 1 change

4h 39m • 1 change

4h 15m • 1 change

4h 15m • 1 change

4h 15m • 1 change

5h 15m • 1 change

4h 15m • 1 change

4h 15m • 1 change

4h 15m • 1 change

5h 15m • 1 change

4h 15m • 1 change

4h 15m • 1 change

4h 15m • 1 change

5h 15m • 1 change

6h 53m • 1 change

4h 15m • 1 change

4h 15m • 1 change

5h 15m • 1 change

4h 15m • 1 change

4h 15m • 1 change

4h 15m • 1 change

5h 15m • 1 change
Want to know about travelling from Lucerne to Frankfurt am Main? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lucerne to Frankfurt am Main. However, there are services departing from Lucerne station and arriving at Frankfurt am Main station via Basel SBB. The journey, including transfers, takes approximately 4h 54m.
Lucerne to Frankfurt am Main train services, operated by Schweizerische Südostbahn AG, depart from Luzern station.
Lucerne to Frankfurt am Main train services, operated by Schweizerische Südostbahn AG, arrive at Frankfurt station.
Book your Lucerne to Frankfurt am Main train tickets online with Schweizerische Südostbahn AG, Deutsche Bahn Intercity (DB IC) and Swiss Federal Railways (SBB CFF FFS).
The distance between Lucerne and Frankfurt am Main is 341.9 km. The road distance is 424 km.
You can take a train from Luzern to Frankfurt via Basel SBB in around 4h 37m.