The average train between Lucerne and Karlsruhe takes 3h 30m and the fastest train takes 3h 2m. The train service runs several times per day from Lucerne to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Lucerne and Karlsruhe. The earliest departure is at 4:54 AM at night, and the last departure from Lucerne is at 11:54 PM which arrives into Karlsruhe at 6:57 AM. All services require a transfer, and take on average 3h 30m. The schedules shown below are for the next available departures.

3h 2m • 1 change

3h 3m • 1 change

3h 2m • 1 change

3h 3m • 1 change

3h 2m • 1 change

3h 27m • 1 change

3h 2m • 1 change

3h 3m • 1 change

3h 2m • 1 change

3h 27m • 1 change

3h 2m • 1 change

3h 3m • 1 change

3h 2m • 1 change

3h 27m • 1 change

3h 2m • 1 change

3h 3m • 1 change
Want to know about travelling from Lucerne to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lucerne to Karlsruhe. However, there are services departing from Lucerne station and arriving at Karlsruhe station via Basel SBB. The journey, including transfers, takes approximately 3h 30m.
Lucerne to Karlsruhe train services, operated by Schweizerische Südostbahn AG, depart from Luzern station.
Lucerne to Karlsruhe train services, operated by Schweizerische Südostbahn AG, arrive at Karlsruhe Hauptbahnhof station.
Book your Lucerne to Karlsruhe train tickets online with Schweizerische Südostbahn AG, Deutsche Bahn Intercity (DB IC) and Swiss Federal Railways (SBB CFF FFS).
The distance between Lucerne and Karlsruhe is 217.9 km. The road distance is 286 km.
You can take a train from Luzern to Karlsruhe Hauptbahnhof via Basel SBB in around 3h 10m.