The average train between Lugano and Karlsruhe takes 5h 26m and the fastest train takes 4h 55m. The train service runs several times per day from Lugano to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Lugano and Karlsruhe. The earliest departure is at 6:00 AM in the morning, and the last departure from Lugano is at 10:02 PM which arrives into Karlsruhe at 6:33 AM. All services require a transfer, and take on average 5h 26m. The schedules shown below are for the next available departures.

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4h 55m • 1 changeWant to know about travelling from Lugano to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lugano to Karlsruhe. However, there are services departing from Lugano station and arriving at Karlsruhe Hauptbahnhof station via Basel SBB station. The journey, including transfers, takes approximately 5h 26m.
Lugano to Karlsruhe train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Lugano station.
Lugano to Karlsruhe train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Karlsruhe Hauptbahnhof station.
Book your Lugano to Karlsruhe train tickets online with Omio.
The distance between Lugano and Karlsruhe is 336.1 km. The road distance is 454 km.
You can take a train from Lugano to Karlsruhe Hauptbahnhof via Basel SBB in around 4h 56m.