The average train between Luino and Mendrisio takes 1h 28m and the fastest train takes 1h 21m. The train service runs several times per day from Luino to Mendrisio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Luino and Mendrisio. The earliest departure is at 5:40 AM in the morning, and the last departure from Luino is at 9:18 PM which arrives into Mendrisio at 11:16 PM. All services require a transfer, and take on average 1h 28m. The schedules shown below are for the next available departures.

1h 38m • 1 change

1h 23m • 1 change

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1h 38m • 1 change

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1h 23m • 1 change

1h 38m • 1 change

1h 23m • 1 change

1h 23m • 1 change

1h 23m • 1 change

1h 38m • 1 change

1h 23m • 1 change

1h 23m • 1 change

1h 23m • 1 change

1h 23m • 1 change

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1h 23m • 1 change
Want to know about travelling from Luino to Mendrisio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Luino to Mendrisio. However, there are services departing from Luino station and arriving at Mendrisio station via Cadenazzo. The journey, including transfers, takes approximately 1h 28m.
Luino to Mendrisio train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Luino station.
Luino to Mendrisio train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Mendrisio station.
The distance between Luino and Mendrisio is 23.9 km. The road distance is 71 km.
You can take a train from Luino to Mendrisio via Cadenazzo in around 1h 31m.