The average train between Luton and Manchester Piccadilly Station takes 4h 45m and the fastest train takes 3h 39m. There is a train service every few hours from Luton to Manchester Piccadilly Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Luton and Manchester Piccadilly Station. The earliest departure is at 12:39 AM at night, and the last departure from Luton is at 11:19 PM which arrives into Manchester Piccadilly Station at 7:35 AM. All services require a transfer at Kettering and take an average of 4h 45m. The schedules shown below are for the next available departures.


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3h 53m • 2 changesWant to know about travelling from Luton to Manchester Piccadilly Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Luton to Manchester Piccadilly Station. However, there are services departing from Luton station and arriving at Manchester Piccadilly Station station via Kettering. The journey, including transfers, takes approximately 4h 45m.
Luton to Manchester Piccadilly Station train services, operated by East Midlands Railways, depart from Luton station.
Luton to Manchester Piccadilly Station train services, operated by East Midlands Railways, arrive at Manchester Piccadilly station.
Book your Luton to Manchester Piccadilly Station train tickets online with East Midlands Railways.
The distance between Luton and Manchester Piccadilly Station is 215.6 km. The road distance is 287 km.
You can take a train from Luton to Manchester Piccadilly via Kettering and Nottingham in around 4h 32m.