The average train between Luxembourg and Prague takes 17h 4m and the fastest train takes 14h 1m. The train service runs several times per day from Luxembourg to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Luxembourg and Prague. The earliest departure is at 6:20 AM in the morning, and the last departure from Luxembourg is at 9:20 PM which arrives into Prague at 6:21 PM. All services require a transfer at Liege-Guillemins and take an average of 17h 4m. The schedules shown below are for the next available departures.




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20h 1m • 4 changesWant to know about travelling from Luxembourg to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Luxembourg to Prague. However, there are services departing from Luxembourg station and arriving at Prague station via Liège-Guillemins. The journey, including transfers, takes approximately 17h 4m.
Luxembourg to Prague train services, operated by Belgian Railways (NMBS/SNCB), depart from Pfaffenthal-Kirchberg station.
Luxembourg to Prague train services, operated by Belgian Railways (NMBS/SNCB), arrive at Praha Hlavni Nadrazi station.
Book your Luxembourg to Prague train tickets online with Belgian Railways (NMBS/SNCB), Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Luxembourg and Prague is 593.7 km. The road distance is 1,018 km.
You can take a train from Pfaffenthal-Kirchberg to Praha Hlavni Nadrazi via Liege-Guillemins, Frankfurt, Nürnberg Hbf, and Schwandorf in around 13h 51m.