The average train between Luxembourg, Gare Centrale and Prague takes 17h 20m and the fastest train takes 12h 48m. The train service runs several times per day from Luxembourg, Gare Centrale to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Luxembourg, Gare Centrale and Prague. The earliest departure is at 7:33 AM in the morning, and the last departure from Luxembourg, Gare Centrale is at 11:33 PM which arrives into Prague at 4:21 PM. All services require a transfer at Trier, Hauptbahnhof and take an average of 17h 20m. The schedules shown below are for the next available departures.




12h 49m • 4 changes
Arrives next day




18h 48m • 4 changes
Arrives next day




18h 48m • 4 changes
Arrives next day




21h 48m • 4 changes
Want to know about travelling from Luxembourg, Gare Centrale to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Luxembourg, Gare Centrale to Prague. However, there are services departing from Luxembourg, Gare Centrale station and arriving at Prague station via Trier, Hauptbahnhof. The journey, including transfers, takes approximately 17h 20m.
Luxembourg, Gare Centrale to Prague train services, operated by Luxembourg Railways (CFL), depart from Luxembourg, Gare Centrale station.
Luxembourg, Gare Centrale to Prague train services, operated by Luxembourg Railways (CFL), arrive at Praha Hlavni Nadrazi station.
Book your Luxembourg, Gare Centrale to Prague train tickets online with Luxembourg Railways (CFL), Deutsche Bahn Regio (DB Regional) and 3 other operators.
The distance between Luxembourg, Gare Centrale and Prague is 596.4 km. The road distance is 846 km.
You can take a train from Luxembourg, Gare Centrale to Praha Hlavni Nadrazi via Trier, Hauptbahnhof, Koblenz Hauptbahnhof, Nürnberg Hbf, and Schwandorf in around 13h 31m.