The average train between Luxembourg (Station) and Mainz takes 4h 25m and the fastest train takes 3h 28m. There is a train service every few hours from Luxembourg (Station) to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Luxembourg (Station) and Mainz. The earliest departure is at 5:10 AM in the morning, and the last departure from Luxembourg (Station) is at 11:33 PM which arrives into Mainz at 7:38 AM. All services require a transfer at Trier, Hauptbahnhof and take an average of 4h 25m. The schedules shown below are for the next available departures.


4h 29m • 2 changes

4h 6m • 2 changes

4h 6m • 2 changes

4h 6m • 2 changes

4h 29m • 2 changes

4h 6m • 2 changes

4h 6m • 2 changes

4h 6m • 2 changes

3h 29m • 2 changes

4h 29m • 2 changes

4h 6m • 2 changes

4h 6m • 2 changes

3h 29m • 2 changes

4h 29m • 2 changes

4h 6m • 2 changes

4h 6m • 2 changesWant to know about travelling from Luxembourg (Station) to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Luxembourg (Station) to Mainz. However, there are services departing from Luxembourg (Station) station and arriving at Mainz station via Trier, Hauptbahnhof. The journey, including transfers, takes approximately 4h 25m.
Luxembourg (Station) to Mainz train services, operated by Luxembourg Railways (CFL), depart from Luxembourg, Gare Centrale station.
Luxembourg (Station) to Mainz train services, operated by Luxembourg Railways (CFL), arrive at Mainz, Hauptbahnhof station.
Book your Luxembourg (Station) to Mainz train tickets online with Luxembourg Railways (CFL), Deutsche Bahn Regio (DB Regional) and 3 other operators.
The distance between Luxembourg (Station) and Mainz is 159.8 km. The road distance is 253 km.
You can take a train from Luxembourg, Gare Centrale to Mainz, Hauptbahnhof via Trier, Hauptbahnhof and Koblenz Hauptbahnhof in around 3h 45m.