The average train between Luxembourg (Station) and Mainz, Hauptbahnhof takes 4h 30m and the fastest train takes 3h 35m. The train service runs several times per day from Luxembourg (Station) to Mainz, Hauptbahnhof. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Luxembourg (Station) and Mainz, Hauptbahnhof. The earliest departure is at 10:33 AM in the morning, and the last departure from Luxembourg (Station) is at 11:33 PM which arrives into Mainz, Hauptbahnhof at 7:46 AM. All services require a transfer at Trier, Hauptbahnhof and take an average of 4h 30m. The schedules shown below are for the next available departures.


4h 6m • 2 changes


4h 6m • 2 changes


4h 6m • 2 changes


4h 6m • 2 changes
Want to know about travelling from Luxembourg (Station) to Mainz, Hauptbahnhof? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Luxembourg (Station) to Mainz, Hauptbahnhof. However, there are services departing from Luxembourg (Station) station and arriving at Mainz, Hauptbahnhof station via Trier, Hauptbahnhof. The journey, including transfers, takes approximately 4h 30m.
Luxembourg (Station) to Mainz, Hauptbahnhof train services, operated by Luxembourg Railways (CFL), depart from Luxembourg, Gare Centrale station.
Luxembourg (Station) to Mainz, Hauptbahnhof train services, operated by Luxembourg Railways (CFL), arrive at Mainz, Hauptbahnhof station.
Book your Luxembourg (Station) to Mainz, Hauptbahnhof train tickets online with Luxembourg Railways (CFL), Deutsche Bahn Regio (DB Regional) and 2 other operators.
The distance between Luxembourg (Station) and Mainz, Hauptbahnhof is 158.9 km. The road distance is 253 km.
You can take a train from Luxembourg, Gare Centrale to Mainz, Hauptbahnhof via Trier, Hauptbahnhof and Koblenz Hauptbahnhof in around 3h 53m.