The average train between Luxembourg and Prague takes 14h 28m and the fastest train takes 12h 48m. There is at least one train per day from Luxembourg to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between Luxembourg and Prague. The earliest departure is at 5:10 AM in the morning, and the last departure from Luxembourg is at 11:33 PM which arrives into Prague at 4:21 PM. All services require a transfer at Trier, Hauptbahnhof and take an average of 14h 28m. The schedules shown below are for the next available departures.




13h 11m • 4 changes



12h 48m • 4 changes



12h 49m • 4 changesArrives next day




16h 48m • 4 changesWant to know about travelling from Luxembourg to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Luxembourg to Prague. However, there are services departing from Luxembourg, Gare Centrale station and arriving at Praha Hlavni Nadrazi station via Trier, Hauptbahnhof station, Koblenz Hauptbahnhof station, Nürnberg Hbf station and Schwandorf station. The journey, including transfers, takes approximately 14h 28m.
Luxembourg to Prague train services, operated by Luxembourg Railways (CFL), depart from Luxembourg, Gare Centrale station.
Luxembourg to Prague train services, operated by Die Länderbahn, arrive at Praha Hlavni Nadrazi station.
Book your Luxembourg to Prague train tickets online with Omio.
The distance between Luxembourg and Prague is 596.5 km. The road distance is 725 km.
You can take a train from Luxembourg, Gare Centrale to Praha Hlavni Nadrazi via Trier, Hauptbahnhof, Koblenz Hauptbahnhof, Nürnberg Hbf, and Schwandorf in around 13h 21m.