The average train between Lyon Airport (LYS) and Prague takes 21h 28m and the fastest train takes 20h 21m. The train service runs several times per day from Lyon Airport (LYS) to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Lyon Airport (LYS) and Prague. The earliest departure is at 10:54 AM in the morning, and the last departure from Lyon Airport (LYS) is at 10:00 PM which arrives into Prague at 6:21 PM. All services require a transfer at Paris Gare de Lyon and take an average of 21h 28m. The schedules shown below are for the next available departures.
Arrives next day




21h 4m • 4 changes
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21h 45m • 4 changes
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23h 27m • 4 changes
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22h 27m • 4 changes
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20h 27m • 4 changes
Arrives next day




20h 21m • 4 changes
Want to know about travelling from Lyon Airport (LYS) to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lyon Airport (LYS) to Prague. However, there are services departing from Lyon Airport (LYS) station and arriving at Prague station via Paris Gare De Lyon. The journey, including transfers, takes approximately 21h 28m.
Lyon Airport (LYS) to Prague train services, operated by Société Nationale des Chemins de fer Français (SNCF), depart from Lyon-Saint Exupery Tgv station.
Lyon Airport (LYS) to Prague train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Praha Hlavni Nadrazi station.
Book your Lyon Airport (LYS) to Prague train tickets online with Société Nationale des Chemins de fer Français (SNCF), Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Lyon Airport (LYS) and Prague is 848 km. The road distance is 1,701 km.
You can take a train from Lyon-Saint Exupery Tgv to Praha Hlavni Nadrazi via Paris Gare de Lyon, Paris Nord, Paris Est, Stuttgart Hbf, Hauptbahnhof, and Muenchen Hbf in around 15h 21m.