The average train between Lyon and Acqui Terme takes 9h 30m and the fastest train takes 6h 45m. The train service runs several times per day from Lyon to Acqui Terme. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Lyon and Acqui Terme. The earliest departure is at 9:31 AM in the morning, and the last departure from Lyon is at 5:23 PM which arrives into Acqui Terme at 8:16 AM. All services require a transfer at Chambery Challes Les Eaux and take an average of 9h 30m. The schedules shown below are for the next available departures.




6h 45m • 4 changes




7h 42m • 4 changes
Arrives next day




13h 54m • 4 changes




6h 45m • 4 changes




7h 42m • 4 changes
Arrives next day




13h 54m • 4 changes




6h 45m • 4 changes




7h 42m • 4 changes
Arrives next day




13h 54m • 4 changes
Want to know about travelling from Lyon to Acqui Terme? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lyon to Acqui Terme. However, there are services departing from Lyon station and arriving at Acqui Terme station via Chambery Challes Les Eaux. The journey, including transfers, takes approximately 9h 30m.
Lyon to Acqui Terme train services, operated by Société Nationale des Chemins de fer Français (SNCF), depart from Lyon Part Dieu station.
Lyon to Acqui Terme train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Alessandria station.
Book your Lyon to Acqui Terme train tickets online with Société Nationale des Chemins de fer Français (SNCF), TGV inOui and Trenitalia.
The distance between Lyon and Acqui Terme is 307.8 km. The road distance is 429 km.
You can take a train from Lyon Part Dieu to Acqui Terme via Chambery Challes Les Eaux, Torino Porta Susa, Torino Lingotto, and Alessandria in around 8h 2m.