The average train between Lyon and Avignon Centre takes 1h 59m and the fastest train takes 1h 12m. There is a train service every few hours from Lyon to Avignon Centre. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Lyon and Avignon Centre. The earliest departure is at 6:28 AM in the morning, and the last departure from Lyon is at 10:06 PM which arrives into Avignon Centre at 6:17 AM. All services require a transfer, and take on average 1h 59m. The schedules shown below are for the next available departures.

1h 37m • 1 change

1h 38m • 1 change

1h 22m • 1 change

1h 42m • 1 change

1h 20m • 1 change

1h 42m • 1 change

1h 42m • 1 change

1h 17m • 1 change

1h 20m • 1 change

1h 42m • 1 change

1h 42m • 1 change

1h 17m • 1 change

1h 20m • 1 change

1h 42m • 1 change

1h 42m • 1 change

1h 17m • 1 change
Want to know about travelling from Lyon to Avignon Centre? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lyon to Avignon Centre. However, there are services departing from Lyon station and arriving at Avignon Centre station via Avignon Tgv. The journey, including transfers, takes approximately 1h 59m.
Lyon to Avignon Centre train services, operated by TGV inOui, depart from Lyon Part Dieu station.
Lyon to Avignon Centre train services, operated by TGV inOui, arrive at Avignon Tgv station.
Book your Lyon to Avignon Centre train tickets online with TGV inOui and Société Nationale des Chemins de fer Français (SNCF).
The distance between Lyon and Avignon Centre is 200.9 km. The road distance is 231 km.
TGV inOui operates a train from Lyon Part Dieu to Avignon Tgv hourly. Tickets cost €45–75 and the journey takes 1h 1m. Société Nationale des Chemins de fer Français (SNCF) also services this route twice daily.