The average train between Lyon and Karlovy Vary takes 19h 3m and the fastest train takes 12h 59m. The train service runs several times per day from Lyon to Karlovy Vary. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Lyon and Karlovy Vary. The earliest departure is at 8:32 AM in the morning, and the last departure from Lyon is at 6:00 PM which arrives into Karlovy Vary at 5:31 PM. All services require a transfer at Strasbourg and take an average of 19h 3m. The schedules shown below are for the next available departures.




12h 59m • 4 changes
Arrives next day




21h 53m • 4 changes
Arrives next day




23h 31m • 4 changes




12h 59m • 4 changes
Arrives next day




21h 53m • 4 changes
Arrives next day




23h 31m • 4 changes




13h 6m • 4 changes
Arrives next day




23h 53m • 4 changes
Arrives next day




23h 31m • 4 changes
Want to know about travelling from Lyon to Karlovy Vary? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lyon to Karlovy Vary. However, there are services departing from Lyon station and arriving at Karlovy Vary station via Strasbourg. The journey, including transfers, takes approximately 19h 3m.
Lyon to Karlovy Vary train services, operated by TGV inOui, depart from Lyon Part Dieu station.
Lyon to Karlovy Vary train services, operated by TGV inOui, arrive at Karlovy Vary station.
Book your Lyon to Karlovy Vary train tickets online with TGV inOui, Arverio Baden-Württemberg and 3 other operators.
The distance between Lyon and Karlovy Vary is 777.2 km. The road distance is 1,050 km.
You can take a train from Lyon Part Dieu to Karlovy Vary via Strasbourg, Stuttgart Hbf, Nuernberg Hbf, Nürnberg Hbf, and Cheb in around 13h 19m.