The average train between Lyon and L'Isle-sur-la-Sorgue takes 4h 36m and the fastest train takes 1h 52m. The train service runs several times per day from Lyon to L'Isle-sur-la-Sorgue. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Lyon and L'Isle-sur-la-Sorgue. The earliest departure is at 6:28 AM in the morning, and the last departure from Lyon is at 10:06 PM which arrives into L'Isle-sur-la-Sorgue at 7:19 AM. All services require a transfer at Avignon Tgv and take an average of 4h 36m. The schedules shown below are for the next available departures.


2h 50m • 2 changes


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2h 14m • 2 changes
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9h 52m • 2 changes


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2h 14m • 2 changes
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9h 52m • 2 changes


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2h 14m • 2 changes
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2h 14m • 2 changes
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10h 8m • 2 changes


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2h 41m • 2 changes


2h 10m • 2 changes
Want to know about travelling from Lyon to L'Isle-sur-la-Sorgue? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lyon to L'Isle-sur-la-Sorgue. However, there are services departing from Lyon station and arriving at L'Isle-sur-la-Sorgue station via Avignon Tgv. The journey, including transfers, takes approximately 4h 36m.
Lyon to L'Isle-sur-la-Sorgue train services, operated by TGV inOui, depart from Lyon Part Dieu station.
Lyon to L'Isle-sur-la-Sorgue train services, operated by TGV inOui, arrive at L'isle-Sur-La-Sorgue - Fontaine-De-Vaucluse station.
Book your Lyon to L'Isle-sur-la-Sorgue train tickets online with TGV inOui, Zou! Lignes Express Régionales and Société Nationale des Chemins de fer Français (SNCF).
The distance between Lyon and L'Isle-sur-la-Sorgue is 204 km. The road distance is 254 km.
You can take a train from Lyon Part Dieu to L'isle-Sur-La-Sorgue - Fontaine-De-Vaucluse via Avignon Tgv and Avignon Centre in around 2h 4m.