The average train between Lyon and Sète takes 2h 27m and the fastest train takes 2h 11m. The train service runs several times per day from Lyon to Sète. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Lyon and Sète. The earliest departure is at 6:40 AM in the morning, and the last departure from Lyon is at 8:10 PM which arrives into Sète at 11:11 PM. All services require a transfer, and take on average 2h 27m. The schedules shown below are for the next available departures.

2h 29m • 1 change

2h 16m • 1 change

2h 22m • 1 change

2h 18m • 1 change

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2h 29m • 1 change

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2h 18m • 1 change

2h 29m • 1 change

2h 20m • 1 change

2h 16m • 1 change

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2h 40m • 1 change

2h 57m • 1 change

2h 16m • 1 change

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2h 29m • 1 change

2h 16m • 1 change

2h 22m • 1 change

2h 18m • 1 change
Want to know about travelling from Lyon to Sète? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lyon to Sète. However, there are services departing from Lyon station and arriving at Sète station via Montpellier Saint-Roch. The journey, including transfers, takes approximately 2h 27m.
Lyon to Sète train services, operated by TGV inOui, depart from Lyon Part Dieu station.
Lyon to Sète train services, operated by TGV inOui, arrive at Montpellier Saint-Roch station.
Book your Lyon to Sète train tickets online with TGV inOui, Société Nationale des Chemins de fer Français (SNCF) and Renfe Viajeros.
The distance between Lyon and Sète is 276.4 km. The road distance is 341 km.
TGV inOui operates a train from Lyon Part Dieu to Montpellier Saint-Roch hourly. Tickets cost €65–110 and the journey takes 1h 55m. Renfe Viajeros also services this route 4 times a day.