The average train between Lyon and Santa Margherita Ligure takes 11h 48m and the fastest train takes 7h 30m. The train service runs several times per day from Lyon to Santa Margherita Ligure. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Lyon and Santa Margherita Ligure. The earliest departure is at 7:50 AM in the morning, and the last departure from Lyon is at 9:50 PM which arrives into Santa Margherita Ligure at 5:02 PM. All services require a transfer at Chambery Challes Les Eaux and take an average of 11h 48m. The schedules shown below are for the next available departures.




7h 30m • 4 changes




9h 44m • 4 changes
Arrives next day




15h 21m • 4 changes
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14h 59m • 4 changes




7h 30m • 4 changes




9h 44m • 4 changes
Arrives next day




15h 21m • 4 changes
Arrives next day




14h 59m • 4 changes




7h 30m • 4 changes




9h 44m • 4 changes
Arrives next day




15h 21m • 4 changes
Arrives next day




14h 59m • 4 changes




7h 30m • 4 changes




9h 44m • 4 changes
Arrives next day




15h 21m • 4 changes
Arrives next day




14h 59m • 4 changes




7h 30m • 4 changes




9h 44m • 4 changes
Arrives next day




15h 21m • 4 changes
Arrives next day




14h 59m • 4 changes




9h 12m • 4 changes




8h 31m • 4 changes




9h 28m • 4 changes




9h 7m • 4 changes
Want to know about travelling from Lyon to Santa Margherita Ligure? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lyon to Santa Margherita Ligure. However, there are services departing from Lyon station and arriving at Santa Margherita Ligure station via Chambery Challes Les Eaux. The journey, including transfers, takes approximately 11h 48m.
Lyon to Santa Margherita Ligure train services, operated by Trenitalia, depart from Lyon Part Dieu station.
Lyon to Santa Margherita Ligure train services, operated by Trenitalia, arrive at Genova P.Za Principe station.
Book your Lyon to Santa Margherita Ligure train tickets online with Trenitalia, Société Nationale des Chemins de fer Français (SNCF) and 2 other operators.
The distance between Lyon and Santa Margherita Ligure is 377.2 km. The road distance is 491 km.
You can take a train from Lyon Part Dieu to S.Margherita L.-Port via Chambery Challes Les Eaux, Torino Porta Susa, Torino Lingotto, and Genova P.Za Principe in around 8h 13m.