The average train between Mühlhausen and Mainz takes 4h 28m and the fastest train takes 4h 20m. There is a train service every few hours from Mühlhausen to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mühlhausen and Mainz. The earliest departure is at 5:24 AM in the morning, and the last departure from Mühlhausen is at 9:00 PM which arrives into Mainz at 1:52 AM. All services require a transfer at Göttingen and take an average of 4h 28m. The schedules shown below are for the next available departures.


4h 23m • 2 changes


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4h 23m • 2 changes


4h 59m • 2 changes


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4h 23m • 2 changes


4h 20m • 2 changes


4h 22m • 2 changes


4h 22m • 2 changes


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4h 20m • 2 changes


4h 22m • 2 changes


4h 22m • 2 changes


4h 22m • 2 changes
Want to know about travelling from Mühlhausen to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mühlhausen to Mainz. However, there are services departing from Mühlhausen station and arriving at Mainz station via Göttingen. The journey, including transfers, takes approximately 4h 28m.
Mühlhausen to Mainz train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mühlhausen station.
Mühlhausen to Mainz train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Frankfurt station.
Book your Mühlhausen to Mainz train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and Süwex.
The distance between Mühlhausen and Mainz is 205.1 km. The road distance is 350 km.
You can take a train from Mühlhausen to Mainz, Römisches Theater via Göttingen and Frankfurt in around 3h 50m.