The train between Mülheim and Karlsruhe takes 3h 13m. The train service runs several times per day from Mülheim to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Mülheim and Karlsruhe. The earliest departure is at 5:46 AM in the morning, and the last departure from Mülheim is at 7:46 PM which arrives into Karlsruhe at 10:59 PM. All services require a transfer, and take on average 3h 13m. The schedules shown below are for the next available departures.

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Want to know about travelling from Mülheim to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mülheim to Karlsruhe. However, there are services departing from Mülheim station and arriving at Karlsruhe station via Karlsruhe Hauptbahnhof. The journey, including transfers, takes approximately 3h 13m.
Mülheim to Karlsruhe train services, operated by Deutsche Bahn Regio (DB Regional), depart from Essen Hbf station.
Mülheim to Karlsruhe train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Karlsruhe Hauptbahnhof station.
Book your Mülheim to Karlsruhe train tickets online with Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Mülheim and Karlsruhe is 290.4 km. The road distance is 392 km.
Deutsche Bahn Intercity (DB IC) operates a train from Essen Hbf to Karlsruhe Hauptbahnhof every 3 hours. Tickets cost €70–300 and the journey takes 2h 59m.