The average train between Mělník and Karlovy Vary takes 5h 17m and the fastest train takes 4h 37m. The train service runs several times per day from Mělník to Karlovy Vary. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mělník and Karlovy Vary. The earliest departure is at 8:24 AM in the morning, and the last departure from Mělník is at 10:24 PM which arrives into Karlovy Vary at 7:01 AM. All services require a transfer, and take on average 5h 17m. The schedules shown below are for the next available departures.

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Want to know about travelling from Mělník to Karlovy Vary? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mělník to Karlovy Vary. However, there are services departing from Mělník station and arriving at Karlovy Vary station via Usti Nad Labem Hlavni Nadrazi. The journey, including transfers, takes approximately 5h 17m.
Mělník to Karlovy Vary train services, operated by RegioJet, depart from Melnik station.
Mělník to Karlovy Vary train services, operated by RegioJet, arrive at Karlovy Vary station.
Book your Mělník to Karlovy Vary train tickets online with RegioJet and České dráhy (ČD).
The distance between Mělník and Karlovy Vary is 114.6 km. The road distance is 190 km.
You can take a train from Melnik to Karlovy Vary via Usti Nad Labem Hlavni Nadrazi in around 3h 56m.