Rome2Rio

Macclesfield to Ayr trains

Find Transport to Ayr

View schedule

Trip Overview

The average train between Macclesfield and Ayr takes 5h 42m and the fastest train takes 4h 58m. There is a train service every few hours from Macclesfield to Ayr. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 42m
Duration
280 mi
Distance
£104
Average price
Hourly
Frequency

Train

best
  1. Take the train from Manchester Piccadilly to Prestontrain train
  2. Take the train from Preston to Glasgow Centraltrain train
  3. Take the train from Glasgow Central to Ayrtrain train
5h 21m
£71–166

Macclesfield to Ayr train times

Trains run hourly between Macclesfield and Ayr. The earliest departure is at 12:14 AM at night, and the last departure from Macclesfield is at 11:25 PM which arrives into Ayr at 8:24 AM. All services require a transfer at Manchester Piccadilly and take an average of 5h 42m. The schedules shown below are for the next available departures.

Departing Tuesday, October 13, 2026

  •  → 

    Cross CountryNorthern Trains LimitedAvanti West CoastScotRail5h 15m • 3 changes

  •  → 

    Avanti West CoastTransPennine ExpressTransPennine ExpressScotRail5h 11m • 3 changes

  •  → 

    Cross CountryNorthern Trains LimitedAvanti West CoastScotRail4h 58m • 3 changes

  •  → 

    Cross CountryNorthern Trains LimitedAvanti West CoastScotRail5h 17m • 3 changes
  • Show more

Departing Wednesday, October 14, 2026

  •  → 

    Avanti West CoastNorthern Trains LimitedAvanti West CoastScotRail10h 9m • 3 changes

  •  → 

    Northern Trains LimitedTransPennine ExpressAvanti West CoastScotRail5h 39m • 3 changes

  •  → 

    Cross CountryNorthern Trains LimitedAvanti West CoastScotRail5h 16m • 3 changes

  •  → 

    Cross CountryNorthern Trains LimitedAvanti West CoastScotRail5h 17m • 3 changes
  • Show more

Departing Thursday, October 15, 2026

  •  → 

    Avanti West CoastNorthern Trains LimitedAvanti West CoastScotRail10h 9m • 3 changes

  •  → 

    Northern Trains LimitedTransPennine ExpressAvanti West CoastScotRail5h 39m • 3 changes

  •  → 

    Cross CountryNorthern Trains LimitedAvanti West CoastScotRail5h 16m • 3 changes

  •  → 

    Cross CountryNorthern Trains LimitedAvanti West CoastScotRail5h 17m • 3 changes
  • Show more

Frequently asked questions

Want to know about travelling from Macclesfield to Ayr? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Macclesfield to Ayr.ExpandLaunch map view
  • Distance: 280 mi
  • Duration: 5h 42m

What companies run services between Macclesfield, England and Ayr, Scotland?

You can take a train from Macclesfield to Ayr via Manchester Piccadilly, Preston, and Glasgow Central in around 5h 21m.

Operators