Macclesfield to Ayr Trains

Trip Overview

The average train between Macclesfield and Ayr takes 5h 45m and the fastest train takes 4h 58m. There is a train service every few hours from Macclesfield to Ayr. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 45m
Duration: 280 mi
Distance: £104
Average price: Hourly
Frequency

Train

best

Take the train from Manchester Piccadilly to Prestontrain
Take the train from Preston to Glasgow Centraltrain
Take the train from Glasgow Central to Ayrtrain

5h 22m

£70–156

Macclesfield to Ayr train times

Trains run hourly between Macclesfield and Ayr. The earliest departure is at 12:14 AM at night, and the last departure from Macclesfield is at 11:39 PM which arrives into Ayr at 1:55 PM. All services require a transfer at Manchester Piccadilly and take an average of 5h 45m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

8:06 PM → 1:09 AM
Arrives next day
5h 3m • 3 changes
11:25 PM → 8:24 AM
Arrives next day
8h 58m • 3 changes

Departing Tuesday, November 3, 2026

12:14 AM → 10:24 AM
10h 9m • 3 changes
6:17 AM → 11:56 AM
5h 39m • 3 changes
7:06 AM → 12:22 PM
5h 16m • 3 changes
8:06 AM → 1:24 PM
5h 17m • 3 changes
Show more

Departing Wednesday, November 4, 2026

12:14 AM → 10:24 AM
10h 9m • 3 changes
6:17 AM → 11:56 AM
5h 39m • 3 changes
7:06 AM → 12:22 PM
5h 16m • 3 changes
8:06 AM → 1:24 PM
5h 17m • 3 changes
Show more

Departing Thursday, November 5, 2026

12:14 AM → 10:24 AM
10h 9m • 3 changes
6:17 AM → 11:56 AM
5h 39m • 3 changes
7:06 AM → 12:22 PM
5h 16m • 3 changes
8:06 AM → 1:24 PM
5h 17m • 3 changes
Show more

Departing Friday, November 6, 2026

12:14 AM → 10:24 AM
10h 9m • 3 changes
6:17 AM → 11:56 AM
5h 39m • 3 changes
7:06 AM → 12:22 PM
5h 16m • 3 changes
8:06 AM → 1:24 PM
5h 17m • 3 changes
Show more

Departing Saturday, November 7, 2026

12:14 AM → 10:24 AM
10h 9m • 3 changes
7:06 AM → 12:23 PM
5h 17m • 3 changes
8:06 AM → 1:22 PM
5h 15m • 3 changes
8:17 AM → 1:51 PM
5h 34m • 3 changes
Show more

Departing Sunday, November 8, 2026

10:38 AM → 4:21 PM
5h 43m • 3 changes
11:40 AM → 5:21 PM
5h 40m • 3 changes
12:08 PM → 5:54 PM
5h 45m • 3 changes
1:06 PM → 6:20 PM
5h 14m • 3 changes
Show more

Frequently asked questions

Want to know about travelling from Macclesfield to Ayr? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.