The average train between Madrid Airport (MAD) and Santander takes 4h 44m and the fastest train takes 4h 33m. The train service runs several times per day from Madrid Airport (MAD) to Santander. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Madrid Airport (MAD) and Santander. The earliest departure is at 7:12 AM in the morning, and the last departure from Madrid Airport (MAD) is at 6:42 PM which arrives into Santander at 11:15 PM. All services require a transfer, and take on average 4h 44m. The schedules shown below are for the next available departures.

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Want to know about travelling from Madrid Airport (MAD) to Santander? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Madrid Airport (MAD) to Santander. However, there are services departing from Madrid Airport (MAD) station and arriving at Santander station via Santander. The journey, including transfers, takes approximately 4h 44m.
Madrid Airport (MAD) to Santander train services, operated by Renfe Cercanias, depart from Madrid Chamartín station.
Madrid Airport (MAD) to Santander train services, operated by Renfe Cercanias, arrive at Santander station.
Book your Madrid Airport (MAD) to Santander train tickets online with Renfe Cercanias and Renfe Viajeros.
The distance between Madrid Airport (MAD) and Santander is 331.1 km. The road distance is 450 km.
Renfe Viajeros operates a train from Madrid Chamartín to Santander every 4 hours. Tickets cost €55–85 and the journey takes 4h 23m.