The average train between Madrid Atocha Station and Santander takes 4h 35m and the fastest train takes 4h 24m. The train service runs several times per day from Madrid Atocha Station to Santander. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Madrid Atocha Station and Santander. The earliest departure is at 7:22 AM in the morning, and the last departure from Madrid Atocha Station is at 6:51 PM which arrives into Santander at 11:15 PM. All services require a transfer at Madrid-Atocha Cercanías and take an average of 4h 35m. The schedules shown below are for the next available departures.

4h 39m • 1 change

4h 41m • 1 change

4h 31m • 1 change

4h 25m • 1 change

4h 39m • 1 change

4h 41m • 1 change

4h 31m • 1 change

4h 25m • 1 change

4h 38m • 1 change

4h 41m • 1 change

4h 31m • 1 change

4h 25m • 1 change

4h 38m • 1 change

4h 41m • 1 change

4h 31m • 1 change

4h 25m • 1 change

4h 43m • 1 change

4h 41m • 1 change

4h 33m • 1 change

4h 28m • 1 change
Want to know about travelling from Madrid Atocha Station to Santander? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Madrid Atocha Station to Santander. However, there are services departing from Madrid Atocha Station station and arriving at Santander station via Santander. The journey, including transfers, takes approximately 4h 35m.
Madrid Atocha Station to Santander train services, operated by Renfe Cercanias, depart from Madrid Chamartín station.
Madrid Atocha Station to Santander train services, operated by Renfe Cercanias, arrive at Santander station.
Book your Madrid Atocha Station to Santander train tickets online with Renfe Cercanias and Renfe Viajeros.
The distance between Madrid Atocha Station and Santander is 340.5 km. The road distance is 449 km.
Renfe Viajeros operates a train from Madrid Chamartín to Santander every 4 hours. Tickets cost €55–85 and the journey takes 4h 23m.