Rome2Rio

Madrid City Center to Rome trains

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Trip Overview

The average train between Madrid City Center and Rome takes 36h 54m and the fastest train takes 36h 49m. The train runs, on average, 4 times per week from Madrid City Center to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

36h 54m
Duration
2,288 km
Distance
€322
Average price
4 times a week
Frequency

Madrid City Center to Rome train times

Trains run 4 times a week between Madrid City Center and Rome. The earliest departure is at 8:10 PM in the evening, and the last departure from Madrid City Center is at 8:30 PM which arrives into Rome at 9:19 AM. All services require a transfer at Barcelona-Sants and take an average of 36h 54m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    Renfe AVERenfe ViajerosTrenitaliaItaloTreno36h 49m • 3 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    Renfe AVERenfe ViajerosTrenitaliaItaloTreno36h 49m • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    Renfe AVERenfe ViajerosTrenitaliaItaloTreno36h 49m • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    OuigoRenfe ViajerosTrenitaliaItaloTreno37h 9m • 3 changes

Frequently asked questions

Want to know about travelling from Madrid City Center to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid City Center to Rome.ExpandLaunch map view
  • Distance: 2,288.2 km
  • Duration: 36h 54m

What companies run services between Madrid City Center, Spain and Rome, Italy?

You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Roma Termini via Barcelona-Sants, Lyon Part Dieu, and Milano Centrale in around 18h 12m.

Operators