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Madrid to Italy trains

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Trip Overview

The average train between Madrid and Italy takes 43h 34m and the fastest train takes 36h 59m. The train runs, on average, 3 times per week from Madrid to Italy. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

43h 34m
Duration
2,290 km
Distance
€325
Average price
3 times a week
Frequency

Madrid to Italy train times

Trains run 3 times a week between Madrid and Italy. The earliest departure is at 12:33 AM at night, and the last departure from Madrid is at 8:20 PM which arrives into Italy at 9:19 AM. All services require a transfer at Madrid-Atocha Cercanías and take an average of 43h 34m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

  •  → 

    Arrives +2 days

    Renfe CercaniasRenfe AVERenfe ViajerosTrenitaliaItaloTreno36h 59m • 4 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    Renfe CercaniasRenfe AVERenfe ViajerosTrenitaliaItaloTreno36h 59m • 4 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    Renfe CercaniasRenfe AVERenfe ViajerosTrenitaliaItaloTreno2d 8h • 4 changes

Frequently asked questions

Want to know about travelling from Madrid to Italy? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid to Italy.ExpandLaunch map view
  • Distance: 2,290 km
  • Duration: 43h 34m

What companies run services between Madrid, Spain and Italy?

You can take a train from Sol to Roma Termini via Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, Barcelona-Sants, Lyon Part Dieu, and Milano Centrale in around 18h 28m.

Operators