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Madrid to Prague trains

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Trip Overview

The train between Madrid and Prague takes 45h 40m. The train runs, on average, 5 times per week from Madrid to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

45h 40m
Duration
2,492 km
Distance
Kč 12,004
Average price
5 times a week
Frequency

Madrid to Prague train times

Trains run 5 times a week between Madrid and Prague. The earliest departure is at 12:40 PM in the afternoon, and the last departure from Madrid is at 12:41 PM which arrives into Prague at 10:21 AM. All services require a transfer at Madrid-Atocha Cercanías and take an average of 45h 40m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

  •  → 

    Arrives +2 days

    Renfe CercaniasRenfe ViajerosTGV inOuiDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)Die Länderbahn45h 41m • 5 changes

Departing Tuesday, November 3, 2026

  •  → 

    Arrives +2 days

    Renfe CercaniasRenfe ViajerosTGV inOuiDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)Die Länderbahn45h 40m • 5 changes

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    Renfe CercaniasRenfe ViajerosTGV inOuiDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)Die Länderbahn45h 40m • 5 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    Renfe CercaniasRenfe ViajerosTGV inOuiDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)Die Länderbahn45h 40m • 5 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    Renfe CercaniasRenfe ViajerosTGV inOuiDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)Die Länderbahn45h 40m • 5 changes

Frequently asked questions

Want to know about travelling from Madrid to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid to Prague.ExpandLaunch map view
  • Distance: 2,491.8 km
  • Duration: 45h 40m

What companies run services between Madrid, Spain and Prague, Czechia?

You can take a train from Sol to Praha Hlavni Nadrazi via Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, Avignon Tgv, Karlsruhe Hbf, Karlsruhe Hauptbahnhof, Nürnberg Hbf, Nürnberg Hbf, and Schwandorf in around 26h 28m.

Operators